Buy Generic Ampicillin (Acillin) Online

How much does Ampicillin cost?

Local pharmacies tend to sell very expensive antibiotics. Today, save an your antibiotic treatment. You can check prices on the net and find the best option in a few minutes. The best way to save is to order this drug from an online pharmacy. For example, we offer you to buy Generic Ampicillin 500mg for only $0.90 per pill and 250 mg for only $0.41 per pill. You can hardly find better price offer on the Internet.

Can I buy Ampicillin online over the counter?

If you buy this drug in your local pharmacy, you will need a prescription. However, if you for some reason cannot see a doctor and you are sure that you need this very antibiotic to treat your infection, you can buy it over the counter. There are a number of trusted and honest online pharmacies that sell medicines Ampicillin without a prescription. Our website is an example of such pharmacy. Here you can buy OTC antibiotics online at low cost.

Mechanism of action

This is a broad-spectrum antibacterial bactericidal agent from the group of semisynthetic penicillins, obtained by acylation of 6-aminopenicillanic acid with an aminophenylacetic acid residue, it is acid resistant. It inhibits peptidoglycan polymerase and transpeptidase, prevents the formation of peptide bonds and disrupts the late stages of the synthesis of the cell wall of a dividing microorganism, which leads to a decrease in the osmotic resistance of the bacterial cell and causes its lysis.

What kind of bacteria does Ampicillin kill?

It is active against aerobic gram-positive bacteria: Staphylococcus spp. (except for penicillinase producing strains), Streptococcus spp., Enterococcus spp., Listeria monocytogenes; aerobic gram-negative bacteria: Neisseria gonorrhoeae, Neisseria meningitidis, Escherichia coli, Shigella spp., Salmonella spp., Bordetella pertussis, some strains of Haemophilus influenzae.

It is effective against penicillinase-producing strains of Staphylococcus spp., all strains of Pseudomonas aeruginosa, most strains of Klebsiella spp. and Enterobacter spp.

What is Ampicillin used for?

It is used to treat many infectious and inflammatory diseases, including:

• respiratory tract infections (including bronchitis, pneumonia, lung abscess);
• infections of ENT organs (including tonsillitis);
• biliary tract infections (including cholecystitis, cholangitis);
• urinary tract infections (including pyelitis, pyelonephritis, cystitis);
• gastrointestinal tract infections (including salmonella carriage);
• gynecological infections;
• infections of the skin and soft tissues;
• peritonitis;
• sepsis, septic endocarditis;
• meningitis;
• rheumatism;
• erysipelas;
• scarlet fever;
• gonorrhea.

When I feel better?

Ampicillin will start working straight away and you should feel better after taking the drug for 2 days. It is important that you take the whole course of antibiotic that has been prescribed by your doctor. Otherwise, the bacterial infection may come back.

What are the side effects of this drug?

• Allergic reactions: peeling of the skin, itching, urticaria, rhinitis, conjunctivitis, Quincke’s edema, fever, arthralgia, eosinophilia, erythematous and maculopapular rash, exfoliative dermatitis, multiforme exudative erythema, including Stevens-Johnson syndrome, reactions similar to serum sickness, in rare cases – anaphylactic shock;
• Digestive system: dysbiosis, stomatitis, gastritis, dry mouth, taste change, abdominal pain, vomiting, nausea, diarrhea, stomatitis, glossitis, impaired liver function, a moderate increase in hepatic transaminases, pseudomembranous enterocolitis;
• Central nervous system: agitation or aggressiveness, anxiety, confusion, behavior change, depression, convulsions (with high-dose therapy);
• Laboratory indicators: leukopenia, neutropenia, thrombocytopenia, agranulocytosis, anemia;
• Other: interstitial nephritis, nephropathy, superinfection (especially in patients with chronic diseases or reduced body resistance), vaginal candidiasis.

How should the medicine be administered?

Take the drug as directed by a doctor. It should be administered orally 30 minutes before or 2 hours after meals. The duration of treatment is determined individually (from 5 days to ≥3 weeks), depending on the characteristics of the disease, the age of the patient, the effectiveness of therapy and the state of renal function. When the clinical signs of the disease disappear, the antibiotic should be taken for another 2-3 days. Do not interrupt the course.

What is the usual dosage for Ampicillin?

The dosage of the drug is determined by a medical specialist depending on the severity of the course, the location of the infection and the sensitivity of the pathogen.

A usual single dose for adults is 250-500 mg, the frequency of administration is 4 times / day. Children weighing up to 20 kg receive 12.5-25 mg / kg every 6 hours.

The duration of treatment depends on the location of the infection and the characteristics of the course of the disease.

Maximum daily dose for adults is 4 g,

Who should not take Ampicillin?

You should not take this drug if you have:

• hypersensitivity to this antiiotic and other β-lactam antibiotics (penicillins, cephalosporins, carbapenems), as well as to any auxiliary components of the drug;
• severe impairment of liver function;
• infectious mononucleosis;
• leukemia;
• HIV infection.

Ampicillin for UTI

This drug is often used for urinary tract infections.

The peculiarity of this antibiotic is that it has hyperactivity in the destruction of pathogenic flora, and it quickly copes with staphylococci, streptococci, E. coli, therefore, it will help with bladder damage too.

Once in the gastrointestinal tract, the drug dissolves and spreads through the circulatory system. The liver and kidneys participate in the metabolism of the drug.

The effect of the penicillin antibacterial drug appears two hours after administration. Healing substances enter the brain and tissues. Bacterial organisms are gradually destroyed. Part of the dose taken is excreted in the urine in 8 hours.

What happens if I take too much ampicillin?

If you exceed the recommended dose of this drug, an overdose can occur.

Symptoms: manifestations of a toxic effect on the central nervous system (especially in patients with renal failure); nausea, vomiting, diarrhea, impaired water-electrolyte balance (as a result of vomiting and diarrhea).

Treatment: gastric lavage, activated charcoal, saline laxatives, drugs to maintain water-electrolyte balance and symptomatic. It is excreted by hemodialysis.

Can you take antibiotics when pregnant?

Pregnant women are allowed to take antibiotics from the group of semisynthetic penicillins, macrolides, and most cephalosporins, if indicated and prescribed by a doctor. Pregnant women CAN NOT use tetracyclines and aminoglycosides since they have a damaging effect on the fetus, they can cause damage to the hearing organ, tooth rudiments and bone tissue.

So, Ampicillin can be used during pregnancy according to indications in those cases when the benefit to the mother outweighs the potential risk to the fetus.

The active substance of the drug is excreted in breast milk in low concentrations. If a woman has to use this antibiotic during lactation, breastfeeding should be stopped.

Ampicillin vs Amoxicillin

These are broad-spectrum antibiotics. They are able to eliminate many types of pathogenic bacteria.

The drugs have an identical mechanism of action, indications and contraindications. Therefore, they are considered interchangeable.

Despite a big number of common features, there are some differences between these drugs. Ampicillin is more quickly excreted from the body and is less absorbed in the tissues. Therefore, the medicine needs to be consumed more frequently.

Amoxicillin is absorbed by 80-95%. Thanks to this, it begins to work faster and lasts longer.

The drugs have about the same cost. Amoxicillin 250 mg costs about $0.42 per pill, and Ampicillin 250 mg costs $0.41 per pill.

Drug interactions

Avoid taking Ampicillin pills with:

• sulbactam;
• bactericidal antibiotics (including aminoglycosides, cephalosporins, cycloserine, vancomycin, rifampicin);
• bacteriostatic antibiotics (including macrolides, chloramphenicol, lincosamides, tetracyclines, sulfonamides);
• indirect anticoagulants;
• probenecid, diuretics, allopurinol, phenylbutazone;
• antacids, glucosamine, laxatives, aminoglycosides;
• ascorbic acid;
• contraceptives.

How do I rebuild my immune system after this antibiotic?

The use of antibiotics can cause harm to the body. So what should be done to prevent unpleasant consequences after a course of antibiotics?

Some natural medicines can enhance immunity. For example, echinacea or lemongrass are excellent folk remedies. In addition, vitamin C is extremely useful. Sometimes decoctions and tinctures of ginseng and eleutherococcus are used. Regular green tea with lemon will also help boost immunity after Ampicillin.

Garlic and onions can also help restore weakened immunity. Apples and grapefruit are also useful.

It’s good to start playing sports. For example, you can go for free swimming or skating or skiing. If it’s hard for you to play sports, you can try to do a ten-minute exercise every morning.

Hardening with a cool or contrast shower is also good.

What foods and drinks to avoid while taking this antibiotic?

Antibiotics can destroy not only pathogenic bacteria but also those that are necessary for the normal functioning of the stomach. As a result, a person may experience abdominal pain after taking these medicines. The use of acidic foods, especially those containing vinegar, will lead to unnecessary strain on the stomach.

During the treatment, it is recommended to eat steamed or boiled dishes, more vegetables, it is better to choose wholemeal bread.

Sweet soda leads to bloating. And in combination with antibiotics, the work of the gastrointestinal tract is even more complicated.

Doctors advise washing antibiotics down only with non-carbonated water and drink 2.5–3 liters throughout the day.

Is it OK to drink alcohol while taking Ampicillin?

This is one of the most frequently asked questions.

The drug is excreted from the body in the urine, about 30% of the drug is metabolized by the liver. A patient combining ampicillin and alcohol should understand that alcohol will distort the pharmacological effect of the drug and the drug will become toxic. Ethanol changes the sensitivity of all organs, their cells and tissues to the action of the drug, making its effect unpredictable.

In the case when this drug and alcohol are simultaneously taken in a short period of time, the consequences for the liver can be extremely undesirable. Decay products are accumulated there, the metabolism is disrupted. The formation of proteins that neutralize the action of toxins is reduced, which adversely affects the liver and the body as a whole.

The use of this drug with alcohol is also contraindicated because it disrupts the functioning of liver enzymes that break down substances. This leads to an uncontrolled effect of the drug. When using the drug, it is recommended to regularly monitor liver functions since the body receives a large load as a result of taking the medicine.

Warnings and precautions

The drug should be used with caution in bronchial asthma, hay fever and other allergic diseases.

In the process of using Ampicillin, systematic monitoring of renal, liver and peripheral blood picture is required.

In case of liver failure, the drug should be used only under the control of liver function.

Patients with impaired renal function require correction of the dosage regimen depending on QC.

When using the drug in high doses in patients with renal failure, toxic effects on the central nervous system can occur.

When using the drug for the treatment of sepsis, a bacteriolysis reaction (the Yarish-Herxheimer reaction) may occur.

If allergic reactions occur during treatment, the drug should be discontinued and desensitizing therapy should be prescribed.

Weakened patients who have to use the drug for a long time may develop superinfection caused by ampicillin-resistant microorganisms.

To prevent the development of candidiasis due to antibiotic treatment, a patient should take nystatin or levorin, as well as B and C vitamins.

Ampicillin reviews

User reviews about this drug are mostly positive.

One of the patients used this drug for the treatment and prevention of colds in the autumn-winter period. The dosage for him was selected by the attending physician. He says that the drug is effective when many of its analogues do not cope with the infection. He also gave this medicine to his son but at a reduced dosage. He also adds that the medication has affordable price. Neither he nor his child had any adverse reactions.

Another patient says that Ampicillin is an excellent and affordable antibiotic that has never failed her. She used it for treating colds. And her husband used it for chronic form of tonsillitis. Neither she nor her husband had any malaise after taking the drug.

Also, you can watch a video review provided by Phc Garrett Campbell, a pharmacist: