Zithromax is a broad-spectrum antibacterial drug. Zithromax drug class is macrolides-azalides. Its antibiotic acts bacteriostatically. By binding to the 50S subunit of ribosomes, it suppresses the peptide translocase at the translation stage, protein synthesis, slows the growth and bacteria reproduction. This antibiotic has a bactericidal effect in high concentrations. It acts on extra- and intracellularly located pathogens. Microorganisms may be initially resistant to the antibiotic action or may become resistant to it.Visit Online Pharmacy
Our online pharmacy is the best way to buy Zithromax online. We include this antibiotic in the online catalog as it obtains high effectiveness for bacterial infections’ treatmnt and prevention. Every customer is capable to arrange an order online without any difficulties. The ordering procedure is simple. It requires to complete several steps to submit an order: choose the product, add it to the shopping cart, fill out personal data, pay for an order. After these steps are completed, you should wait for a parcel for a certain period of time. The delivery terms are specified in the shopping cart.
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Yes, you can. You can make an order online without sending us a prescription. We deprive you of this unpleasant procedure. The only advice we can give our custmers is to visit a physician. The physician will give recommendations in relation to dosage, side effects, and contraindications. After that, you can buy Zithromax over the counter using our service.
Generic Zithromax (Azithromycin) is a broad-specrum antibiotic. It is released in tablets, suspension. This antibiotic is applied in different bacterial infections’ treatment and prevention. The table below will show to what bacteria this antibiotic is effective.
|Aerobic gram-positive microorganisms||Aerobic gram-negative microorganisms||Anaerobic microorganisms||Other|
|Staphylococcus aureus (methylcillin-sensitive)||Haemophilus influenzae||Clostridium perfringens||Chlamydia trachomatis|
|Streptococcus pneumoniae (penicillin-sensitive)||Haemophilus parainfluenzae||Fusobacterium spp.||Chlamydia pneumoniae|
|Streptococcus pyogenes||Legionella pneumophila||Prevotella spp.||Chlamydia psittaci|
|Moraxella catarrhalis||Porphyromonas spp.||Mycoplasma pneumoniae|
|Pasteurella multocida||Mycoplasma hominis|
|Neisseria gonorrhoeae||Borrelia burgdoferi|
Moderately sensitive or insensitive bactria: aerobic gram-positive microorganisms: Streptococcus pneumoniae (moderately sensitive or resistant to penicillin).
Resistant bacteria are: aerobic gram-positive microorganisms: Enterococcus faecalis, Staphylococci spp. (methicillin-resistant), Staphylococus aureus (including methicillin-sensitive strains), Staphylococus pneumoniae, Staphylococcus spp. Group A (beta hemolytic). Zithromax is not active against strains of gram-positive bacteria resistant to erythromycin.
Doctor recommends to use Zithromax in the following diagnosis and conditions:
Azithromycin (Generic Zithromax) is a broad-spectrum antibacterial agent, a representative of the macrolide antibiotic group, or azalides. Zithromax inhibits the synthesis of bacterial protein and thus fights against microbial infections, especially the respiratory tract. In high concentrations, this antibiotic has a bactericidal effect. It acts on extra- and intracellular pathogens. Azithromycin creates high concentrations in lung tissues, body fluids, has a convenient dosage regimen. It has a favorable price-effectiveness ratio. Zithormax is active against gram-positive and some anaerobic microorganisms, but inactive against gram-positive bacteria that are resistant to erythromycin.
|Infectious diseases||infrequently – candidiasis (including the mucous membrane of the oral cavity and genitals), pneumonia, pharyngitis, gastroenteritis, respiratory diseases, rhinitis; unknown frequency – pseudomembranous colitis.|
|The blood and lymphatic system||infrequently – leukopenia, neutropenia, eosinophilia; very rarely – thrombocytopenia, hemolytic anemia.|
|The side of metabolism||infrequently – anorexia.|
|Allergic reactions||infrequently – angioedema, hypersensitivity reaction; unknown frequency – anaphylactic reaction.|
|The nervous system||often – headache; infrequently – dizziness, violation of taste, paresthesia, drowsiness, insomnia, nervousness; rarely – agitation; unknown frequency – hypesthesia, anxiety, aggression, fainting, convulsions, psychomotor hyperactivity, loss of smell, perversion of smell, loss of taste, myasthenia gravis, delirium, hallucinations.|
|The side of the organ of vision||infrequently – impaired vision.|
|The hearing organ and labyrinth disorders||infrequently – hearing impairment, vertigo; unknown frequency – hearing impairment up to deafness and / or tinnitus.|
|The cardiovascular system||infrequently – a feeling of palpitations, flushing of the face; unknown frequency – decreased blood pressure, increased QT interval on the ECG, pirouette type arrhythmia, ventricular tachycardia.|
|Ihe respiratory system||infrequently – shortness of breath, nosebleeds.|
|The digestive system||very often – diarrhea; often – nausea, vomiting, abdominal pain; infrequently – flatulence, dyspepsia, constipation, gastritis, dysphagia, bloating, dryness of the oral mucosa, belching, ulcers of the oral mucosa, increased secretion of the salivary glands; very rarely – discoloration of the tongue, pancreatitis.|
|The liver and biliary tract||infrequently – hepatitis; rarely – impaired liver function, cholestatic jaundice; unknown frequency – liver failure (in rare cases with a fatal outcome mainly due to severe impairment of liver function), liver necrosis, fulminant hepatitis.|
|The skin and subcutaneous tissues||infrequently – skin rash, itching, urticaria, dermatitis, dry skin, sweating; rarely – photosensitivity reaction; unknown frequency – Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme.|
|The musculoskeletal system||infrequently – osteoarthritis, myalgia, back pain, pain in the neck; unknown frequency – arthralgia.|
|The kidneys and urinary tract||infrequently – dysuria, pain in the kidneys; unknown frequency – interstitial nephritis, acute renal failure.|
|The genitals and mammary gland||infrequently – metrorrhagia, impaired testicular function.|
|Local reactions||often – pain and inflammation at the injection site.|
|Other||infrequently – asthenia, malaise, fatigue, swelling of the face, chest pain, fever, peripheral edema.|
Take this antibiotic carefully in the following cases:
Zithromax is prescribed for pregnant women in the second and third trimester of pregnancy (before childbirth) to prevent the development of bacteria in the vagina and cervix, which can affect the pregnancy course. Infections caused by certain microorganisms of the female genital tract can cause health problems in the mother and baby and lead to premature birth.
This review includes 8 randomized clinical trials in which approximately 4,300 women in their second or third trimester of pregnancy took part. We found that antibiotics did not reduce the risk of premature rupture of the membranes (one clinical trial, low quality of evidence), or the risk of premature birth (6 clinical trials, high quality of evidence). The preterm birth rate was reduced in pregnant women whose previous birth was premature, and there was an imbalance of bacteria in the vagina (bacterial vaginosis) during pregnancy.
There was no decrease in the frequency of preterm birth in pregnant women with a previous history of preterm birth without bacterial imbalance during real pregnancy (two clinical trials). The incidence of postpartum endometritis, or uterine infection after childbirth, was reduced overall (three clinical trials, medium quality of evidence), as well as in a clinical trial involving high-risk women whose previous birth was premature (one clinical trial, average quality of evidence).
Therefore, there is no reason to prescribe antibiotics to all pregnant women in the second or third trimester of pregnancy to prevent the adverse effects of infections on pregnancy outcomes.
Watch the video about antibiotics during the first tremester:
Zithromax has been used in clinical practice for almost two decades. During this time, various prescription regimens of this unique macrolide have been proposed and studied for various nosologies, including pediatrics, so in different publications, you can find different doses and duration of treatment courses.
First of all, you should focus on the basic rules for Zithromax use in children:
Azithromycin in the form of capsules or coated tablets should be taken whole without chewing or opening the shell. Therefore, these dosage forms are usually not suitable for children weighing lower than 45 kg.
In children, azithromycin should be used in the form of a suspension, which ensures dosing accuracy and ease of use.
The world-recommended regimens for Zithromax for respiratory infections (otitis media, sinusitis, community-acquired pneumonia and streptococcal tonsillopharyngitis) in children are based on the results of randomized controlled comparative clinical trials and, accordingly, differ with the listed nosologies. The following are US FDA-approved regimens for administering azithromycin for respiratory tract infections in children, as the official information provided in the American Pharmacopoeia (USP) contains the most comprehensive data on the specifics of prescribing the drug in pediatric practice.
For the treatment of acute otitis media in children in the United States, three modes of drug use are recommended:
The therapeutic concentration of azithromycin lasts up to 5-7 days after the last dose. Zithromax is excreted 50% through the intestines, 6% by the kidneys.
It is contraindicated to take the following group of medications with Zithromax: