Generic Cipro (Ciprofloxacin) Online

How does it work?

Ciprofloxacin is abroad-spectrum antimicrobial agent from the group of fluoroquinolones. It has a bactericidal effect. It works by suppressing DNA gyrase and inhibits the synthesis of bacterial DNA.

Ciprofloxacin is active against gram-negative aerobic bacteria: enterobacteria (Escherichia coli, Salmonella spp., Shigella spp., Citrobacter spp., Klebsiella spp., Enterobacter spp., Proteus mirabilis, Proteus vulgaris, Serratia marcescens, Hafnia alvei, Provwardsella spp. Proviellaella., Morganella morganii, Vibrio spp., Yersinia spp.), Other gram-negative bacteria (Haemophilus spp., Pseudomonas aeruginosa, Moraxella catarrhalis, Aeromonas spp., Pasteurella multocida, Plesiomonas shigelloides, Campyloibacter jepp.) some intracellular pathogens (Legionella pneumophila, Brucella spp., Chlamydia trachomatis, Listeria monocytogenes, Mycobacterium tuberculosis, Mycobacterium kansasii, Mycobacterium avium intracellulare); Gram-positive aerobic bacteria: Staphylococcus spp. (Staphylococcus aureus, Staphylococcus haemolyticus, Staphylococcus saprophyticus, Staphylococcus hominis), to a lesser extent Streptococcus spp. (Streptococcus pyogenes, Streptococcus agalactiae).

Most methicillin-resistant staphylococci are resistant to ciprofloxacin.

The sensitivity of bacteria Streptococcus pneumoniae, Enterococcus faecalis is moderate.

Corynebacterium spp., Bacteroides fragilis, Pseudomonas cepacia, Pseudomonas maltophilia, Clostridium difficile, Nocardia asteroides, Ureaplasma urealyticum are resistant to the drug.

The effect of the drug on Treponema pallidum is not well understood.

How much is Cipro?

The cost of this drug varies from pharmacy to pharmacy. Local pharmacies tend to sell exclusively expensive branded versions of ciprofloxacin. However, you have a perfect opportunity to save on your antibiotic by ordering it from an online pharmacy. Internet stores offer the most affordable drugs. This is mainly due to the fact that online pharmacies sell generic antibiotics that are less costly. You can explore all price offers online without leaving your home. For example, we sell Generic Cipro online for only $0.71 per pill.

Can you get Cipro without a prescription?

If you buy antibiotics in your local pharmacy, they will ask you to show a prescription from your local health care provider. However, if you want to get this antibiotic over the counter, you can buy Generic Cipro from our online pharmacy. However, before you buy and take this medicine, we still insist that you consult a doctor, even if you have already bought this antibiotic for the same condition and it helped you. Bear in mind that self-medication can be dangerous, especially when it comes to treatment of infections.

What is Cipro used for?

The drug is used to treat infectious and inflammatory diseases caused by microorganisms sensitive to ciprofloxacin.

Adults:

• lower respiratory tract infections: acute and chronic (in the acute stage) bronchitis, pneumonia, bronchiectatic disease, infectious complications of cystic fibrosis;
• ENT infections: acute sinusitis;
• kidney and urinary tract infections: cystitis, pyelonephritis;
• genital infections, including adnexitis, gonorrhea, prostatitis;
• abdominal infections (bacterial infections of the gastrointestinal tract, biliary tract);
• infections of the skin and soft tissues: infected ulcers, wounds, burns, abscesses, phlegmon;
• infections of bones and joints: osteomyelitis, septic arthritis;
• sepsis and peritonitis;
• infection against the background of immunodeficiency due to treatment with immunosuppressive drugs or in patients with neutropenia;
• prevention and treatment of pulmonary anthrax.

Children and adolescents (5 to 17 years old):

• therapy of complications caused by Pseudomonas aeruginosa in children with pulmonary cystic fibrosis;
• prevention and treatment of pulmonary anthrax (infection of Bacillus anthracis)

Allergic reactions

Cipro is usually tolerated well, however, in some cases, it may cause the following side effects:

• Central and peripheral nervous system: dizziness, headache, fatigue, insomnia, tremor, anxiety, “nightmare” dreams, peripheral paralgesia (anomaly in the pain perception), increased sweating, increased intracranial pressure, including benign intracranial hypertension, confusion, depression (which can lead to self-harming behavior, such as suicidal behavior / thoughts, as well as attempted suicide or successful suicide), hallucinations, as well as other manifestations of psychotic reactions (which can lead to self-harming behavior, such as suicidal acts / thoughts, as well as attempted suicide or successful suicide), migraine, fainting, cerebral artery thrombosis, agitation, disorientation, paresthesia and dysesthesia, hypesthesia, convulsions, vertigo, impaired coordination of movements, impaired gait, hyperesthesia, and peripheral neurosis neuropeuropathy bouts of epilepsy;
• Sensory organs: taste disturbances, visual disturbances, tinnitus, hearing loss, violation of smell, violation of color perception, hearing impairment;
• Cardiovascular system: tachycardia, other heart rhythm disturbances, lowering blood pressure, lengthening of the QT interval, ventricular arrhythmias (including Pirouette type);
• Digestive system: nausea, vomiting, diarrhea, abdominal pain, flatulence, decreased appetite and the amount of food taken, cholestatic jaundice (especially in patients with past liver diseases), pancreatitis, hepatitis, hepatonecrosis;
• Hemopoietic system: eosinophilia, leukopenia, granulocytopenia, thrombocytopenia, anemia, leukocytosis, thrombocytosis, hemolytic anemia, neutropenia, agranulocytosis, pancytopenia, inhibition of bone marrow hematopoiesis, serum sickness;
• Urinary system: hematuria, crystalluria (primarily with alkaline urine and low diuresis), dysuria, polyuria, urinary retention, albuminuria, glomerulonephritis, urethral bleeding, decreased nitrogen excretory function of the kidneys, interstitial nephritis, renal failure;
• Respiratory system: respiratory failure (including bronchospasm);
• Allergic reactions: skin itching, hives, the formation of blisters, accompanied by bleeding, small nodules forming scabs, drug fever, pinpoint hemorrhages on the skin (petechiae), swelling of the face or larynx, shortness of breath, eosinophilia, increased photosensitivity, vasculitis, erythema nodosum, erythema multiforme exudative (including Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell’s syndrome), anaphylactic reactions, anaphylactic shock;
• Laboratory indicators: increased activity of “liver” transaminases and alkaline phosphatase, hyperbilirubinemia, a change in the content of prothrombin (including hypoprothrombinemia), hyperglycemia or hypoglycemia, an increase in amylase activity, hypercreatininemia;
  Other: face flushing, arthralgia, arthritis, tendovaginitis, tendon ruptures (mainly Achilles), asthenia, myalgia, increased muscle tone, muscle weakness, exacerbation of symptoms of myasthenia gravis, superinfection (candidiasis, pseudomembranous colitis), acute generalized pustular exanthema, increased international normalized ratio (in patients receiving vitamin K antagonists).

Contraindications

Do not take Cipro if you have any of the following conditions:

• hypersensitivity to ciprofloxacin and other drugs of the quinolone group and auxiliary substances;
• children’s age (up to 18 years – until the completion of the skeleton formation process, except for the treatment of complications caused by Pseudomonas aeruginosa, in children with pulmonary cystic fibrosis from 5 to 17 years;
• prevention and treatment of pulmonary form anthrax),
• simultaneous administration with tizanidine (risk of a pronounced decrease in blood pressure, drowsiness),
• pregnancy, lactation (breastfeeding).

Use with caution: severe cerebral arteriosclerosis, cerebrovascular accident, mental illness, epilepsy, severe renal and / or liver failure, old age, increased risk of prolonged QT interval or pirouette type arrhythmia (eg, congenital prolongation of the QT interval), heart disease (heart failure, myocardial infarction, bradycardia), electrolyte imbalance (for example, with hypokalemia, hypomagnesemia), the simultaneous use of drugs that extend the interval QT (including antiarrhythmic classes IA and III, tricyclic antidepressants, macrolides, antipsychotics), simultaneous use with CYP450 1A2 isoenzyme inhibitors (including theophylline, methylxanthine, caffeine, duloxetine, clozapine, ropinirole, olanzapine), patients with ananesthesia indications of tendon damage during previous treatment with quinolones, myasthenia gravis, glucose-6-phosphate dehydrogenase deficiency.

How to take Cipro properly?

Tablets should be taken orally, regardless of meals, without chewing, with a small amount of liquid. If the drug is used on an empty stomach, the active substance is absorbed faster. In this case, tablets should not be washed down with dairy products or drinks containing calcium (for example, milk, yogurt, juices with a high content of calcium). Calcium contained in ordinary food does not affect the absorption of ciprofloxacin.

What dosage of Cipro is right for me?

Patients with urinary tract infections take 0.125-0.5 g 2 times a day, in more severe cases – up to 0.75 g 2 times a day. The course of treatment usually lasts 5 to 15 days. Patients with gonorrhea take 0.5 g once.

Dosage and treatment with Cipro for various diseases:

• Urinary tract infections (acute uncomplicated). Dose: Cipro 500 mg, once a day. Duration of treatment: 3 days;
• Urinary tract infections (mild / moderate). Dose: 500 mg, once a day. Duration of treatment: 7-14 days;
• Urinary tract infections (severe / complicated). Dose: 1000 mg, once a day. Duration of treatment: 7-14 days;
• Chronic bacterial prostatitis (mild / moderate). Dose: 1000 mg, once a day. Duration of treatment: 28 days;
• Lower respiratory tract infections (mild / moderate). Dose: 1000 mg, once a day. Duration of treatment: 7-14 days;
• Infections of the lower respiratory tract (severe / complicated). Dose: 1500 mg, once a day. Duration of treatment: 7-14 days;
• Acute sinusitis (mild / moderate). Dose: 1000 mg, once a day. Duration of treatment: 10 days.

Drug interactions

Avoid taking Cipro with any of the following drugs:

• didanosine;
• antacids, preparations containing ions of aluminum, zinc, iron, magnesium;
• metoclopramide;
• uricosuric agents;
• other antimicrobials (beta-lactams, aminoglycosides, clindamycin, metronidazole);
• theophylline (and other xanthines, such as caffeine);
• oral hypoglycemic drugs;
• indirect coagulants;
• cyclosporine;
• NSAIDs (excluding acetylsalicylic acid).

Planning pregnancy, being pregnant or breastfeeding

The drug is contraindicated for use during pregnancy and breastfeeding. In the early and late stages of pregnancy, taking ciprofloxacin drugs leads to damage to the child’s joints. Therefore, doctors prescribe the drug with extreme caution and only when the benefit of taking the drug for the mother significantly exceeds the likely risk to the fetus.

What happens if you take too much Cipro?

Symptoms of an overdose: nausea, vomiting, confusion, mental agitation.

Treatment: specific antidote unknown. It is necessary to carefully monitor the patient’s condition, conduct gastric lavage and other emergency measures, ensure an adequate flow of fluid.

In order to prevent the development of crystalluria, it is recommended to monitor renal function, including pH and acidity of urine.

Compatibility with alcohol

It is not recommended taking Cipro with alcohol. In combination with alcohol, the effect of ciprofloxacin is markedly reduced. Penetrating into the bloodstream, and then into the liver, the antibiotic exerts a heavy load on the cells of the organ, so it can no longer cope with other toxic substances. Therefore, alcohol remains in the liver in its raw form, accumulates, and leads to intoxication of the whole organism.

Changes may occur in the liver. They are manifested by the following reactions:

• convulsions;
• headaches;
• disorders of the central nervous system;
• disorders of the heart and blood vessels;
• a sharp increase or decrease in blood pressure;
• kidney failure, etc.

Warning and precautions

If you notice pains in the tendons or the first signs of tendovaginitis, treatment should be discontinued due to the risk of inflammation and rupture of the tendon. Patients with epilepsy, a history of seizures, vascular diseases and organic brain damage should take the drug only for health reasons. If severe and prolonged diarrhea occurs during or after treatment, the diagnosis of pseudomembranous colitis should be excluded, which requires immediate withdrawal of the drug. During the treatment period, it is necessary to ensure the intake of a sufficient amount of fluid while observing normal diuresis. During the treatment period, contact with direct sunlight should be avoided. Patients taking the antibiotic should be careful when driving a car and engaging in other potentially hazardous activities that require increased attention and speed of psychomotor reactions.

Cipro reviews

Most user reviews available online are positive.

One of the health care specialists says that Cipro is the best antibiotic as it is easy to use. According to him, the drug is effective for bronchitis, tracheitis, gastrointestinal disease, genitourinary system diseases. The expected effect is speedy, there are no side effects. He says the drug is well tolerated.
Another medical experts writes that ciprofloxacin is a good antibiotic. She often prescribes this drug and its combination with other drugs to patients both before preparation for surgery and in the postoperative period.

One more doctor mentiones that he usually prescribes this antibiotic for purulent-inflammatory diseases of the teeth and oral cavity.

According to a female user, she took Cipro to treat bladder inflammation. A course lasted 10 days and she took 2 tablets per day. The drug helped her, inflammation was not detected after 10 days. One more patient wrote that he used this drug to treat acute bronchitis and he was quite satisfied with the result. He also mentioned that this drug was quite cheap.